Non - Cardiogenic Pulmonary Oedema(NCPE)[also known as Transfusion Related Acute Lung Injury(TRALI)]
Unusual
Chills, fever, cough, cyanosis, hypotension and increasing pulmonary distress shortly after being insufficient to produce circulatory overload.
Mild cases may resolve within a few days.
Severe cases may rapidly progress to pulmonary failure.
Exclude heart failure, volume overload, bacteria sepsis and myocardial infraction.
1. Stop transfusion.
2. Supportive respiratory treatment as required.
3. Supportive haemodynamic treatment.
If the reaction is due to recipient's anti - leucocyte antibody, leuco - poor blood components may be used.
