AETIOLOGY
Anaphylactic & Anaphylctoid Reactions
INCIDENCE
Less Common
CLINICAL CULTURE
Anaphylactic : sudden onset symptoms which include coughing, dyspnoea, nausea, vomiting, bronchospasm, flushing of skin, chest pain, abdominal cramps, hypotension, diarrhoea, shock, loss of consciousness and death.
Anaphylactoid : Similar to allergic reaction but may also include peri-orbital oedema.
MANAGEMENT
1. Stop transfusion : Do not restart after controlling the symptoms.
2. Keep i/v line open with normal saline.
3. Inj. Epinephrine (0.2 to 0.5 ml of 1:1000 solution) immediately.
4. Corticosteroids or aminophyline may be necessary.
5. Maintain airway patency.
6. Stabilise vital signs by appropriate treatment.
PREVENTION
In a patient with a history of anahylactic reaction to blood or plasma containing component use plasma-free RBC.
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