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AETIOLOGY Anaphylactic & Anaphylctoid Reactions |
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INCIDENCE Less Common |
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CLINICAL
CULTURE Anaphylactic : sudden onset symptoms which include coughing, dyspnoea, nausea, vomiting, bronchospasm, flushing of skin, chest pain, abdominal cramps, hypotension, diarrhoea, shock, loss of consciousness and death. Anaphylactoid : Similar to allergic reaction but may also include peri-orbital oedema. |
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MANAGEMENT 1. Stop transfusion : Do not restart after controlling the symptoms. 2. Keep i/v line open with normal saline. 3. Inj. Epinephrine (0.2 to 0.5 ml of 1:1000 solution) immediately. 4. Corticosteroids or aminophyline may be necessary. 5. Maintain airway patency. 6. Stabilise vital signs by appropriate treatment. |
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PREVENTION In a patient with a history of anahylactic reaction to blood or plasma containing component use plasma-free RBC. |